Bioidentical hormone replacement therapy (BHRT) has emerged as a cutting-edge approach to address hormone deficiencies and improve quality of life. As leaders in the field, Rejuvenate HRT Clinic specializes in customized BHRT to help both men and women feel healthy, energetic, and youthful again.
Bioidentical hormones are chemically identical replicas of the hormones naturally produced by the human body. As we age, our hormone production declines, leading to unpleasant symptoms.
Bioidentical hormone therapy involves supplementing decreasing hormones to maintain optimal levels. Since bioidentical hormones match human hormones molecule for molecule, they are well-tolerated with fewer side effects than traditional treatment.
At Rejuvenate HRT Clinic, we offer personalized therapy based on your symptoms and hormone test results rather than a one-size-fits-all approach. Our expert physicians take the time to understand your health goals and design a tailored regimen to rebalance your hormones for maximum benefits.
The first step is determining which hormones are out of balance through blood, saliva, or urine tests. We measure levels of key hormones including:
Based on the test findings, our bioidentical hormone doctor will recommend an appropriate treatment plan involving bioidentical hormone creams, patches, pellets or injectables.
Ongoing testing ensures hormone levels are optimized for each patient's needs down to the most precise dosage. We also provide nutritional advice and track progress to deliver the greatest benefits.
Traditional hormone replacement therapy utilizes synthetic or animal hormones with a different molecular makeup than human hormones. This causes more pronounced side effects including fluid retention, weight gain, and increased risk of certain cancers.
In contrast, bioidentical hormones:
For these reasons, bioidentical hormone replacement (BHRT) is safer and produces more favorable patient outcomes overall.
The following table summarizes the key differences:
| Feature | Bioidentical HRT | Traditional HRT |
|---|---|---|
| Source | Soybeans, yams, other plant compounds | Synthetic or animal hormones |
| Chemical structure | Identical to human hormones | Different than human hormones |
| Side effects | Fewer side effects due to identical properties | More side effects due to mismatch with the body's hormones |
| Dosage | Lower doses needed due to efficient utilization | Higher doses often required |
| Cancer risk | No increased risk of breast or uterine cancer | May increase cancer risk |
| Monitoring | Frequent testing ensures optimal hormone balance | Less testing between patient visits |
Table: Comparison between bioidentical hormone therapy and traditional hormone replacement approaches
While bioidentical hormones are clearly the superior option, finding an experienced bioidentical hormone doctor is essential for safe and effective treatment.
Founded in 2012 by Dr. Sarah Johnson, Rejuvenate HRT Clinic brings over 30 years of expertise in endocrinology and hormone therapy for both men and women. What sets us apart is our commitment to:
✅ Fully personalized care - We don't use a templated approach but tailor therapy to your unique needs
✅ Precision dosing - Through blood and saliva testing, we determine the exact hormones and amounts to prescribe
✅ Highest quality hormones - We use only natural, bioidentical hormones from reputable pharmacies
✅ Integrative therapies - We combine hormone adjustment with lifestyle changes for total wellbeing
✅ Ongoing support - Your progress will be regularly monitored and therapy adjusted accordingly
We also stand out for our warm, compassionate manner and taking ample time to address each patient's concerns. We consider it a privilege to help people look and feel their best regardless of age or gender.
If you relate to any of the following symptoms, declining hormones may be to blame:
In women:
In men:
In younger individuals:
Bioidentical hormone therapy can effectively ease these symptoms and restore wellbeing. With an individualized regimen, most patients report:
❇️ Balanced mood - More calm, less anxiousness
❇️ Healthy weight - Muscle gain, fat loss
❇️ High vitality - More energy, stamina
❇️ Better cognition - Sharper focus, clear thinking
❇️ Deeper sleep - Fall asleep and stay asleep
❇️ Increased libido – Heightened sexual desire/function
❇️ Bone protection – Reduced fracture risk
❇️ Disease prevention – Lower risk of age-related conditions
The following sections provide more details on the role key hormones play in the body and specific benefits of bioidentical replacement.
As the primary male sex hormone, testosterone impacts a range of bodily processes in both men and women. Levels peak during the late teens to early twenties then gradually decline by 1% per year from age 30 onwards. This slow depletion causes changes including:
Physical:
Mental/Emotional:
Sexual:
Left untreated, worsening testosterone deficiency symptoms severely undermine one's vitality and enjoyment of life.
Bioidentical hormone treatment with customized testosterone creams, gels or injections can effectively turn back the clock 5, 10 or even 15 years for men deficient in this master-hormone.
With testosterone therapy from Rejuvenate HRT Clinic, patients can reasonably expect:
💪 Increased muscle mass and strength – Make faster gains through exercise
💪 Decreased fat – Noticeable reduction in belly and chest fat
🔋 High energy – Feel less sluggish and fatigued
🧠 Sharper cognition – Think more clearly with improved memory
😊 Balanced moods – Less anxiety, irritability and depression
🏋️♂️ Enhanced performance – Excel during workouts or sports
🤩 Heightened libido – Interest in sex and improved sexual function
😌 Better sleep – Fall asleep faster, stay asleep
🦴 Bone protection – Build bone density to prevent osteoporosis
🌡️ Stable temperature – Avoid unpleasant hot flashes
With bioidentical testosterone tailored to your personal needs, you'll look better, feel stronger, and lead a more vigorous life again!
The primary female sex hormone, estrogen plays a vital role in reproductive health and regulating menstrual cycles. Produced mainly in the ovaries, estrogen production declines sharply during perimenopause and menopause – typically ages 45-55. This fall causes uncomfortable symptoms like:
🔥 Hot flashes – Sudden sensations of intense warmth lasting 1-5 minutes
🥵 Night sweats – Severe hot flashes disrupting sleep
🧠 Brain fog – Poor memory, fuzzy thinking, trouble focusing
😢 Mood changes – Increased anxiety, irritability and depression
🚽 Bladder issues – Urinating much more frequently
😱 Panic attacks – Episodes of sudden terror, fear, chest tightness
💢 Headaches – More frequent and severe
🛌 Insomnia – Difficulty falling/staying asleep
While manageable at first, worsening symptoms severely impact one's professional performance and personal life over months and years.
Bioidentical hormone replacement in the form of FDA-approved BiEst cream, patches or tablets can effectively minimize troublesome menopausal symptoms.
BiEst (bi-estrogen) contains a blend of *estradiol and estriol – the two types of estrogen naturally made by the body. Therapy works by:
💉 Optimizing estrogen levels to avoid the sharp drop 🧊 Regulating temperature centers in the brain 🛏️ Reducing night sweats for better sleep 😌 Easing anxiety and mood swings 😊 Restoring mental clarity and memory
At Rejuvenate HRT Clinic, we carefully prescribe the lowest effective BiEst dosage through blood testing. If needed, we pair estrogen with natural progesterone to offset any risks to the uterine lining.
With our customized approach, patients report profound relief allowing them to feel like themselves again.
The adrenal glands and thyroid also have crucial roles regulating our metabolism, immunity, reproduction and handling stress.
The walnut-sized adrenal glands above each kidney produce over 50 hormones, with cortisol and DHEA being most vital.
Cortisol helps control blood sugar levels and metabolism. High cortisol causes weight gain and muscle loss.
DHEA (dehydroepiandrosterone) supports immunity, energy levels, mood and sexual desire. DHEA peaks around age 25 then declines.
Chronic stress, poor diet, infections, and aging drain the adrenals over time. Symptoms of adrenal exhaustion include:
😫 Fatigue – Feel constantly rundown
🚫 Slow recovery from exercise
🤒 Frequent illnesses – Catch every bug
🍩 Carb cravings – Need sweets for quick energy
☕️ Caffeine dependence to function
😴 Insomnia early, better sleep late – initial burst keeping you up then crash later
🥺 Anxiety – Unprovoked worry and dread
👿 Irritability – Quick to anger and lash out
💤 Afternoon slump – Feel drained midday
If the adrenal glands are taxed, we provide nourishment and bioidentical DHEA to rehabilitate their function.
The butterfly-shaped thyroid produces metabolites of tyrosine including triiodothyronine (T3) and thyroxine (T4). Known as TH, these hormones regulate:
⚖️ Metabolism – Heart rate, weight management
💇 Hair growth
🥶 Body temperature
🧠 Mood, cognition and concentration
🚏🚶 Energy levels and endurance
Thyroid issues often result from autoimmune Hashimoto's disease but also frequently accompany menopause and andropause. Patients experience:
🐌 Sluggish metabolism – Feel cold all the time, gain weight
😓 Fatigue – Constantly exhausted
😫 Aches and pains
🧠 Mental fog – Forgetful with cloudy thinking
🤯 Moodiness – More irritable and short-tempered
💔 Heart palpitations – Fluttery sensations
If thyroid hormones come back low, we provide bioidentical T3/T4 thyroid medication at precise dosages to resolve deficiency signs.
The pea-sized pineal gland nestled deep in the brain produces the hormone melatonin in response to darkness. Known as the "hormone of darkness," melatonin helps regulate:
🥱 Sleep cycles – Signals it's time for bed
🛌 Sleep quality – Maintains restorative REM/deep sleep
📈 Immune function – Key defender against infections
As we pass age 40, melatonin levels often decline. Common signs include:
😵💫 Insomnia – Trouble falling and staying asleep
🥱 Feeling drowsy midday – Fighting the urge to nap
😣 Needing sleep aids – Relying on medication nightly
The usual culprit is too much light exposure at night from phones/devices which shuts off melatonin production earlier. This plays havoc with the body's inner clock.
Our providers may prescribe low-dose bioidentical melatonin capsules to reestablish healthy sleep patterns or use light therapy to shift circadian rhythms earlier.
We deliver bioidentical hormones through several approaches:
Absorbed through the skin, creams provide steady hormone levels. They're easy to adjust by varying dosage frequency.
Also administered transdermally, medicated patches adhere to the skin and release fixed amounts over days. Gels are quickly absorbed.
Dense hormone pellets are surgically implanted under the hip skin and dissolve slowly. Pellets maintain stable hormone levels for ~5 months.
Some bioidentical hormones are taken orally as capsules, liquids or sublingual tablets with reasonable absorption.
For testosterone, select estrogens and growth hormone therapy, deep muscular injections every 7-21 days offer convenient dosing.
Each approach has different pros and cons regarding dosing flexibility, administration, duration and expense. Our experienced physicians discuss options to meet patient needs and preferences.
While bioidentical hormone replacement effectively minimizes unpleasant deficiency symptoms, we strongly encourage patients to support their therapy through healthy lifestyle habits.
General recommendations include:
🍏 Nutrition - Follow an anti-inflammatory diet emphasizing fruits, vegetables, lean meats, fish, nuts/seeds and whole grains. Limit sugar, refined carbs and alcohol which provoke inflammation. Drink plenty of filtered water.
🏋️ Exercise – Engage in consistent moderate exercise like brisk walking, swimming or strength training most days of the week. This reduces hormone resistance promoting weight loss.
😴 Restful sleep – Turn off screens 1 hour before bedtime and make your bedroom pitch black and cool for better sleep quality.
☀️ Vitamin D – Get ample sun exposure (~15 minutes daily) and take ~2000 IU vitamin D3 supplementation especially during winter months.
🧘 Mindfulness – Adopt stress reduction practices like yoga, meditation, deep breathing and journaling. Chronic stress raises cortisol exacerbating imbalance.
🛑 Smoking cessation – Quit smoking and avoid secondhand smoke which deplete hormones and create hormone resistance.
Following an integrative approach combining bioidentical hormones and therapeutic lifestyle changes delivers superior results on lab tests and subjective symptom scores.
Research shows bioidentical hormone patients see improvements in body fat composition, bone density, lipid profiles, cardiovascular markers, libido and wellbeing (Wierman 2016).
At Rejuvenate HRT Clinic in Denver, each new patient undergoes an extensive two-hour initial consultation focused on their symptoms, health history and goals.
Our physicians then order laboratory testing to assess hormone, nutrition and metabolism markers. Follow-up consultations of 60 minutes review the results and map out a treatment plan.
We take great pride in truly listening and seeking to understand the challenges each person faces from hormonal decline. Every therapy recommendation aims to improve quality of life – not just normalize lab values!
Ongoing follow-up consultations to review lab work and adjust dosing ensure treatment remains highly personalized. We also provide incredible patient support through our hand-picked Wellness Coaches.
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